In order to bring you the best possible user experience, this site uses Javascript. If you are seeing this message, it is likely that the Javascript option in your browser is disabled. For optimal viewing of this site, please ensure that Javascript is enabled for your browser.
Did you know that your browser is out of date? To get the best experience using our website we recommend that you upgrade to a newer version. Learn more.

We use cookies to optimise the design of this website and make continuous improvement. By continuing your visit, you consent to the use of cookies. Learn more

More vigilant blood pressure surveillance in woman after early-onset preeclampsia?

Comment by Paul Leeson, EACPR Exercise, Basic and Translational Research Section

Unique Blood Pressure Characteristics in Mother and Offspring After Early Onset Preeclampsia
M. Lazdam et al.
Hypertension 2012; 60: 1087; doi: 10.1161/HYP.0b013e31827679ab

Pregnancy and Heart Disease

Women who develop preeclampsia very early in their pregnancy are more likely to have a family history of preeclampsia and develop preeclampsia again in subsequent pregnancies.

A reason for this may be that these women carry a biological predisposition to hypertensive disorders. In support of this hypothesis Lazdam et al. have recently identified that women who suffer early onset preeclampsia have distinct differences in their blood pressure when they are not pregnant.
Compared with women who developed preeclampsia late in pregnancy or had normal blood pressure levels, those who had early-onset disease had persistently higher blood pressures for several weeks after delivery and, then, over the next decade their blood pressure increased out of proportion to their blood pressures during the pregnancy.

Interestingly, the authors also studied the offspring of the pregnancy and found they had around 6 mmHg higher systolic blood pressure by 10 years of age compared to both those born to late-onset disease and following normotensive pregnancies.

These observations raise the possibility that a diagnosis of early onset preeclampsia may be an important risk marker that should prompt more vigilant blood pressure surveillance to prevent disease?