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HFA Philip Poole Wilson Lecture

Heart Failure 2016 Congress News

2015 saw the launch of the first Philip Poole Wilson lecture which honours the memory of Philip Poole Wilson (1943-2009), a British cardiologist. Besides being a great advocate for research in heart failure, he also served as President of the European Society of Cardiology (ESC) from 1994 to 1996. Each year, this lecture will be given by a specialist who has made a difference for the future generations of heart failure specialists. This year Luigi Tavazzi (GVM Care & Research - E.S. Health Science Foundation, Maria Cecilia Hospital, Cotignola, Italy) Heart Failure 2016 Congress Ambassador, will deliver the lecture ‘New scenarios in medical science’.

The Philip Poole Wilson lecture will be given as a keynote of the Young Investigator Awards session, Prof. Tavazzi explains.

“My lecture will touch upon the latest developments in information technology and their possible application in medicine. Topics that are of specific interest to the youngest generation.”

One of the fields that will be highly influenced by technology is epidemiology. Prof. Tavazzi believes that pragmatic epidemiology will have an increasing role in the prevention and management of cardiovascular diseases, particularly in heart failure.

“So far, epidemiology is based on administrative data or clinical/ biological data collected from just a handful of centers. It has taken years and years to gather sufficient data, to be meaningfully analysed and put to use. Nowadays a systematic collection of everyday data through Electronic Health Recording (HER) systems from universal national/regional health  networks, in general or specific settings, is possible. The United States are a prime example as they are making huge investments in this particular area. Moreover, nearly every individual owns a smart phone or an individual electronic device which, connected by sensors to the body, can capture and forward remotely biological signals allowing the collection of volumes of health data that are increasing by order of magnitude, in times sharply decreasing. The time of big data has actually also come to medicine. Such a systematic approach should generate a sort of day by day, pragmatic epidemiology, a potential permanent source of scientific knowledge and a platform for an evidence based management of the national health systems. However, a proportionally tremendous effort is needed for adequately handling and appropriately interpreting all this information. This includes for instance the individual genome as component of the citizen’s personal health dossier.”

Prof Tavazzi strongly stresses that a strict cooperation is essential between scientists, managers and politicians to use such a historical opportunity at best.

Another important topic that he will discuss is observational research, such as registries.

“Nowadays, the observational research is going to be incorporated in medical practice as one of the primary activities. The Northern European countries have been at the forefront of the process in the last decades. In the present days, most international Medical Scientific Societies are creating networks of centers collecting validated data on the most important morbidities. The Cardiovascular Medical Societies are most active in proposing and testing new methodologies in observational science, and heart failure is the most prominent area of interest.”

The second part of Prof. Tavazzi’s lecture will move to the experimental research by focusing on a specific area of the immense field of cell pluripotency.

“Our cells are sensitive to electromagnetic fields (EMF) and acoustic or subsonic vibrations permeating our life environment, now recordable at the atomic and molecular levels”, Prof Tavazzi says. “The EMF are able to afford efficient DNA and cellular reprogramming. Our cells are also generating microcurrents in response to energetic signals, that are dispersed into the environment, but can be sampled and conveyed back to targeted body areas or isolated human stem cells. This is a sort of autologous signal capable to induce (stem)cell pluripotency and restore the intrinsic body’s self-healing potential, particularly by the population of resident stem cells.”

A longterm  non-invasive therapeutic application of physical energies to restore the vital potential of the diseased human cells and tissues is a dream presently investigated.

Prof. Tavazzi, ESC Gold Medalist, is an active contributor of such ambitious research as his impressive track record reveals. He has contributed to many important randomized controlled trials either as chairman or co-chairman (GISSI-studies, HORIZON), as a member of the steering committee (CARE-HF, ValHeft, SENIORS, SENSE-HF, PROSPECT, OPERA), as a member of the executive committee (SHIFT) or as DSMB member or chair (EMPHASIS, TOSCA, CANDHEART, HORIZON, AUGMENT HF, CYCLE). He served as member or chair of several national/ international observational studies and ESC Comittees/Working Groups and recently as chairman of the Euro-Observational Research Program (EORP) of the ESC. Additionally, he serves as a member of the editorial board of several peer reviews journal including the European Journal of Heart Failure. He is author/co-author of more than 600 publications and 24 books (participation).

Listen to Prof. Tavazzi give the Philip Poole Wilson as a keynote speech of the  Young Investigator Award: Basic Science session on Sunday, May 22 at 14:15, in the Agora.

View the session programme and access the resources on SP&P